Study Cores

Principal Investigator

Ken Marek, MD, President and Senior Scientist, Institute of Neurodegenerative Disorders


Study Cores

Bioanalytics Core

The Bioanalytics Core will perform some of the biomarker verification studies identified by the Steering Committee and will be working closely with the PPMI Biorepository in monitoring and performing quality control on collected samples.

Co-Investigators: Brit Mollenhauer, MD and Douglas Galasko, MD


Bioinformatics Core

The Bioinformatics Core has designed and will maintain the PPMI study database. This Core is also responsible for the programming of the study website.

Principal Investigator: Arthur W. Toga, PhD
Laboratory of Neuro Imaging (LONI)


Biorepository Core

The PPMI Biorepository will receive, store and distribute biospecimens collected throughout the course of the study.

Principal Investigator: Tatiana Foroud, PhD
Department of Medical and Molecular Genetics
Indiana University School of Medicine


Clinical Core

The Clinical Core is responsible for site management, as well as the collection, tracking and performance of quality control on clinical data.

Principal Investigator: Karl Kieburtz, MD, MPH
Clinical Trials Coordination Center (CTCC)
University of Rochester


DTI Analysis Core

The DTI Analysis Core will lead the analyses that will be performed on the MRI/DTI data.

Principal Investigator: Duygu Tosun-Turgut, PhD
Department of Radiology, University of California San Francisco


Genetics Coordination Core

The Genetics Coordination Core provides operational support for the Genetic Cohort of the study.

Principal Investigator: Tatiana Foroud, PhD
Department of Medical and Molecular Genetics
Indiana University School of Medicine


Genetics Core

The Genetics Core will analyze DNA collected from study subjects.

Principal Investigator: Andrew Singleton, PhD
Laboratory of Neurogenetics
National Institute on Aging/NIH


Imaging Core

The Imaging Core will receive, aggregate and perform quality control on all imaging data in the study. This Core will also perform preliminary analyses of imaging data, as directed by the Steering Committee.

Principal Investigator: John Seibyl, MD
Institute of Neurodegenerative Disorders


Statistics Core

The Statistics Core will lead the statistical analyses that will be performed on the PPMI data and samples.

Principal Investigator: Christopher S. Coffey, PhD
Clinical Trials Statistical and Data Management Center
University of Iowa


Advanced Analytics Core
The Advanced Analytics Core leverages a multi-disciplinary approach to quantitatively explore, evaluate, and predict disease trajectory, risk factors, and subtypes.

Principal Investigator: Chris Baglieri
Blackfynn, Inc.


To communicate with a Principal Investigator at one of the Study Cores, contact us.

Sponsoring Organization

PPMI is sponsored by The Michael J. Fox Foundation for Parkinson?s Research, which is coordinating all study activities and working closely with the Principal Investigator and Study Cores.

Sohini Chowdhury, Deputy CEO
Mark Frasier, PhD, Senior Vice President, Research Programs
Todd Sherer, PhD, Chief Executive Officer
Vanessa Arnedo, Director, Research Partnerships
Anna Naito, PhD, Associate Director, Research Programs
Alyssa Reimer, Associate Director, Research Partnerships
Tara Hastings, Associate Director, Research Partnerships
Addie Clark, Officer, Research Partnerships