Study Design


The PPMI study was designed with comprehensive insight from researchers throughout the PD and biomarkers fields. The study aims to produce both the most comprehensive and long-ranging dataset available for biomarker discovery work throughout the PD community. PPMI has built a dynamic, extensive infrastructure that is widely recognized as a valuable model for biomarker research. Recognizing the opportunity to leverage the established infrastructure of the study, the PPMI model is being utilized to follow multiple cohorts of interest to the scientific community.

This section of the site is designed to provide insight into the study design and to provide access to primary study documents, study statistics and general questions about the rationale for the protocol.

PPMI was designed with a strong focus on developing standardized protocols, policies, systems and processes. To achieve successful implementation of this across many clinical sites and cores, the study leadership has led the development of an extensive study protocol, data collection standards and processes, and data and biospecimen use agreements and policies. All of these documents support the collection, transfer and storage of clinical and imaging data and biological samples.

Click here to access PPMI Research Documents and SOPs.


Stats Forum

A stats forum exists for investigators who are interested in accessing or who have accessed the PPMI database to get additional information about the dataset or to ask questions about it. This area of the site is moderated by the PPMI Statistics Core, led by Christopher Coffey, PhD.