Welcome to the Parkinson’s Progression Markers Initiative (PPMI), a landmark observational clinical study to comprehensively evaluate cohorts of significant interest using advanced imaging, biologic sampling and clinical and behavioral assessments to identify biomarkers of Parkinson’s disease progression.
PPMI is taking place at clinical sites in the United States, Europe, Israel, and Australia. Data and samples acquired from study participants will enable the development of a comprehensive Parkinson’s database and biorepository, which is currently available to the scientific community to conduct field-changing research.
PPMI is made possible by the concerted efforts of a number of collaborators. This study is sponsored by The Michael J. Fox Foundation for Parkinson’s Research.
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Religious Action Center of Reform Judaism Director Rabbi Jonah Pesner: “This study provides an important opportunity to help potentially stamp out an insidious disease and reflects the Jewish imperative toward pikuach nefesh, the saving of a life.”
PPMI will now be following individuals with a GBA mutation as part of the Genetic Cohort. In addition to being linked to Parkinson’s disease, GBA mutations can cause Gaucher disease. A GBA mutation is more common among certain populations, specifically those of Ashkenazi (Eastern European) Jewish descent. Read the full press release here.
PPMI is proud to be well-represented at the 12th International Conference on Alzheimer’s and Parkinson’s Diseases and Related Neurological Disorders (AD/PD 2015), which is being held March 18-22 in Nice, France. Find out when PPMI data will be presented.
For the second year, PPMI is participating in the Biomarkers Across Neurodegenerative Diseases (BAND) program. The Alzheimer’s Association, Alzheimer’s Research UK, The Michael J. Fox Foundation and the Weston Brain Institute announce a collaborative Request for Applications to stimulate analyses across Alzheimer’s disease (AD), Parkinson’s disease (PD) and other neurodegenerative diseases.
Enrolled participants can take part in the PPMI Study Update Call Series. Calls take place on a quarterly basis and feature presentations and Q&A with leading researchers and study team members. View the 2015 call schedule.