Welcome to the Parkinson’s Progression Markers Initiative (PPMI), a landmark observational clinical study to comprehensively evaluate cohorts of significant interest using advanced imaging, biologic sampling and clinical and behavioral assessments to identify biomarkers of Parkinson’s disease progression.
PPMI is taking place at clinical sites in the United States, Europe, Israel, and Australia. Data and samples acquired from study participants will enable the development of a comprehensive Parkinson’s database and biorepository, which is currently available to the scientific community to conduct field-changing research.
PPMI is made possible by the concerted efforts of a number of collaborators. This study is sponsored by The Michael J. Fox Foundation for Parkinson’s Research.
Learn more about Who We Are.
Enrolled participants can take part in the PPMI Study Update Call Series. Calls take place on a quarterly basis and feature presentations and Q&A with leading researchers and study team members. View the 2015 call schedule.
An archive of study protocols and schedules of activities is now available. The archive provides a clear history of the study’s progress and serves as a resource for researchers using the PPMI database and biospecimens.
Qualified researchers can request access to PPMI biospecimens through the rolling application process. Mark your calendars with the 2015 schedule to ensure timely submission and review.
Andrew Singleton, PhD, principal investigator of the PPMI Genetics Core at the National Institute on Aging/NIH was the latest guest speaker in the PPMI Study Update Call series for enrolled participants. You can now listen to this call about PPMI, genetics, and PD on the For Enrolled Participants page.
PPMI’s principal investigator, Ken Marek, MD, and The Michael J. Fox Foundation’s Mark Frasier, PhD held the PPMI Progress Update: Available Data and Biosamples webinar, covering an overview of PPMI, some initial findings, and the process for accessing the PPMI clinical data, imaging data, and biospecimens. A recording of the webinar is now available.