PPMI has also expanded to generate fibroblasts and induced pluripotent stem cell (iPSC) lines from PPMI subjects. An inventory of the cell lines is available through the PPMI database and can be reviewed by investigators interested in requesting PPMI cell lines. Unlike PPMI biospecimens, PPMI cell lines may be used for PD biomarker discovery studies. In addition, PPMI cell lines may be used for research in other neurodegenerative disease areas.
Application Process to Request Cell Lines
Researchers interested in requesting cell lines are encouraged to review the Process for Requesting Cell Lines. Researchers requesting cell lines must agree to the Cell Lines Use Agreement and the Publications Policy. Click the button below to read more about the Process for Requesting Cell Lines and to begin the Request Process.
Before starting the cell line request process, click here to download the application template.
Ongoing Sample Analyses and Other Resources
A listing of preliminary analyses specified by the Steering Committee and performed by PPMI cores, as well as analyses performed by additional investigators will be listed in the Ongoing Analyses section of this site. Investigators who are granted samples from PPMI agree to update this information annually, providing the research public with a comprehensive list of the latest findings coming out of PPMI.
Researchers who are interested in reviewing the PPMI collection, processing and storage protocols for cell lines should review the cell lines manuals in the Research Documents and SOPs section of the PPMI website