Tag Archive | "Study protocol"

Update to PPMI Protocol

PPMI?s updated study protocol (version 11.0) allows for subjects enrolled in the Parkinson?s Disease (PD) and Healthy Control cohorts to continue participation in PPMI beyond month 60.  Subjects in these two cohorts consenting to amendment 10 will be followed through month 96 (V15). Subjects in the PD cohort will continue with annual in person visits […]

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New Feature: Archive of Study Protocols

An archive of study protocols and schedules of activities is now available. The archive provides a clear history of the study's progress and serves as a resource for researchers using the PPMI database and biospecimens.

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PPMI Protocol Updated

PPMI was designed to be adaptable to changing needs, targets, and opportunities in research. In reflection of this, PPMI recently updated its study protocol to include new and revised procedures and assessments. View a summary of the latest changes.

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Summary of the PPMI Genetic Cohort Kick-Off Meeting

The PPMI Genetic Cohort Kick-Off Meeting took place on September 16th & 17th in New York, NY. Site Investigators, study staff, Study Core members, and members of the Steering Committee attended the two-day meeting to discuss the launch of the new Genetic Cohort in PPMI. The meeting covered the rationale for the new cohort, lessons learned from previous studies, and operational procedures.

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PPMI to host Genetics Cohort Kick-Off meeting in New York, NY in September

Next month, PPMI Steering Committee members have invited clinical site teams and study core members to attend a two-day meeting in New York to kick-off the launch of the new Genetic Cohort. The meeting will feature presentations from the study cores, an overview of the amended study protocol, and recruitment strategies.

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PPMI Study to add new Genetic Cohort

The PPMI Steering Committee has decided to expand PPMI to include a Genetic Cohort. It is hoped that this additional cohort, called G-PPMI, will provide researchers with the opportunity to examine biomarker progression in this unique group of subjects. The PPMI study has built a robust infrastructure of sites and cores with well-defined processes to ensure standardization across sites that will be to support the Genetic Cohort. G-PPMI is currently in the planning phase.

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New feature: Case Report Forms by Group and Visit

A new feature has been added to the Research Documents & SOPs section of the website. Case Report forms are now available for download from the website as complete visit packets for Prodromal, De Novo PD, and Control participants.

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PPMI launches new prodromal cohort

PPMI has launched a new study arm to enroll and follow a prodromal PD cohort with the goal of providing researchers with the opportunity to examine biomarker progression prior to the onset of motor symptoms. This new cohort seeks to enroll subjects without Parkinson?s disease who have at least one of the following characteristics: hyposmia, REM sleep behavior disorder, LRRK2 genetic mutation.

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PPMI Ancillary Studies in Full Swing

An update on the integration of SWEDD's, TAP-PD, fMRI, tracking MCI and dementia, and inclusion of exercise assessment as ancillary studies in PPMI

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Update on New Prodromal Cohort Added to PPMI

This March, the Parkinson?s Progression Markers Initiative (PPMI) will launch a new study arm to enroll and follow a prodromal Parkinson?s disease (PD) cohort.   Defining a pre-diagnostic or prodromal phase for PD presents both an immediate challenge ? how to reliably identify individuals during this prodromal period at high risk to phenoconvert to PD ? […]

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