Tag Archive | "Study Cores"

Genetics Participant Study Update Call

Andrew Singleton, PhD, principal investigator of the PPMI Genetics Core at the National Institute on Aging/NIH was the latest guest speaker in the PPMI Study Update Call series for enrolled participants. You can now listen to this call about PPMI, genetics, and PD on the For Enrolled Participants page.

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Participant Study Update Call on PPMI Imaging

The audio from the latest PPMI Participant Study Update Call has just been posted. On the call, the principal investigator of the PPMI Imaging Core, John Seibyl, MD of Molecular Neuroimaging, LLC, discusses the role of imaging in PPMI. Listen to this call and find an archive of the past calls here.

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Core Focus: the Genetics Coordination Core

The PPMI study cores are responsible for a wide range of study needs including analyzing, storing, and performing quality control measures on the study data and specimens, providing supplies, guidance, and support to study sites, and performance and study management. In this core spotlight, Genetics Coordination Core Principal Investigator Tatiana Foroud, PhD and her team explain their role in PPMI.

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Understanding the Genetic Widespread Recruitment Initiative

The Widespread Recruitment Initiative (WRI) is an internet-based recruitment tool that allows potential PPMI participants to be screened, consented and provided with LRRK2 testing without having to visit a PPMI site. Find out how the process works.

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PPMI Annual Meeting 2014 Summary

On May 6 and 7, PPMI held its 2014 Annual Investigators Meeting in New York, NY. Participants included site investigators and coordinators, study and sponsor staff, industry partners, and Steering Committee, Patient Advisory Committee, and study core members representing 15 countries and about 60 companies and organizations. View this year's presentations.

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Summary of the PPMI Genetic Cohort Kick-Off Meeting

The PPMI Genetic Cohort Kick-Off Meeting took place on September 16th & 17th in New York, NY. Site Investigators, study staff, Study Core members, and members of the Steering Committee attended the two-day meeting to discuss the launch of the new Genetic Cohort in PPMI. The meeting covered the rationale for the new cohort, lessons learned from previous studies, and operational procedures.

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Summary of the PPMI 2013 Annual Meeting in New York, NY

The 2013 PPMI Annual Meeting took place on May 7th & 8th in New York, NY. Site investigators, study staff, industry partner representatives, patient advisory committee members, Study Core members, and members of the Steering Committee gathered for a holistic overview of what has already been accomplished and what the future holds for PPMI.

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Dr. John Q. Trojanowski to Present on PPMI at the International Conference on Alpha-Synuclein in Parkinson?s Disease and Related Neurodegenerative Diseases

Dr. Trojanowski, PI of the PPMI Bioanalytics Core will present on PPMI during the Biomarkers session at the International Conference on Alpha-Syunclein in Parkinson?s Disease on March 3, 2013 at 9:45 AM in Dubai. His talk will focus on the early Synuclein analyses that have been done in PPMI and preliminary findings on a subset of PPMI samples.

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MDS Presentation on PPMI- Association between CSF biomarkers and clinical phenotype of early Parkinson’s disease

We found that the level of tau proteins (t-tau and p-tau181) and a-syn in CSF of these untreated PD patients were significantly lower than those of HC, and that CSF a-syn concentration was significantly correlated with the concentrations of CSF tau proteins. Further investigations are planned to test the predictive performance of the biomarkers for disease progression.

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PPMI 2012 Annual Meeting Summary

The PPMI Annual Meeting recently took place in New York City. Access to the presentations that were made at the meeting are now available.

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