Tag Archive | "Scientific Publication"

Diffusion Tensor Imaging Reflects Degree of Motor Symptoms

In a recent publication in Movement Disorders, Zhang, et al. used PPMI data and found that diffusion tensor imaging (DTI) detected neural fiber abnormalities in people with Parkinson's disease (PD) and that the degree of deviation from normal neural fiber integrity is associated with the severity of motor symptoms in patients.

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Morphological Changes in the PD Brain

Frontiers in Neuroscience recently published an article by Garg, et al. comparing changes in the volume of different regions of the brain between healthy controls and people with Parkinson's using structural MRIs from PPMI and the University of British Columbia.

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SWEDDs and Nonmotor Symptoms Publication

In a recent paper in Movement Disorders, researchers sought to better understand SWEDDs compared to people with Parkinson's and healthy controls (HCs) by comparing the nonmotor symptoms for each group using the PPMI baseline data. Certain symptoms, like orthostatic hypotension, were found to be more common in SWEDDs than in PD participants.

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Results Published on Cognitive Performance and Neuropsychatric Symptoms

In a paper published in Movement Disorders, Weintraub, et al. investigate the prevalence of cognitive impairment and neuropsychiatric symptoms (NPS), such as depression, apathy, and anxiety, in early, unmedicated people with Parkinson's compared with healthy controls (HCs) using the PPMI baseline data.

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New Publication on SPECT Imaging and Executive Function

A new study using PPMI data was published in the journal Movement Disorders exploring the relationship between cognitive impairment and dopaminergic deficits in unmedicated Parkinson's patients.

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Daytime Sleepiness and Fatigue Associated with Cognitive Impairment

A recent publication in the journal Parkinsonism and Related Disorders used PPMI data to find that more severe daytime sleepiness and fatigue are associated with greater cognitive impairment. The study's researchers used PPMI data as well as data from two other studies in order to examine this relationship across the different stages of Parkinson's.

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First Longitudinal Findings: Psychiatric Symptoms More Common in Untreated PD Patients than Controls

The first longitudinal findings from PPMI have been published. Researchers from the University of Pennsylvania affiliated with PPMI published in the journal Neurology that depression, anxiety and fatigue are more common in newly diagnosed Parkinson?s disease patients compared to the general population.

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Publication Associates RBD with Worse Motor Symptoms in PD

New research from Johns Hopkins University using PPMI baseline data from Parkinson's patients has found that those experiencing REM sleep behavior disorder (RBD) symptoms have more severe motor symptoms than patients without RBD. The findings were published in the journal Tremor and Other Hyperkinetic Movements.

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Research Using PPMI Data Examines Cortical Thinning and Initial Cognitive Decline in Early Parkinson’s (Neurology)

Neurology published research investigating the link between cortical thinning and cognitive decline in early Parkinson?s disease using the PPMI data. Daniel Weintraub, PhD, the chair of the PPMI Cognitive/Behavioral Working Group, co-authored the paper.

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Check out the improved Publications & Presentations page

The Publications & Presentations page on the website has just been revamped. The goal of the new design is to streamline the process by which researchers can submit a manuscript for Data & Publications Committee (DPC) review, submit a poster or presentation to be posted to the website, and browse the archive of PPMI presentations and publications.

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