Tag Archive | "Pre-motor cohort"

PPMI focus on LRRK2 gene profiled in two South Florida newspapers

Earlier this month, two Florida newspapers reported on the prevalence of LRRK2 genetic mutations in the Ashkenazi Jewish population and the need for them to receive genetic testing and participate in PPMI. Dr. Stuart Isaacson, director of PPMI site Parkinson?s Disease and Movement Disorders Center of Boca Raton, was interviewed.

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PPMI launches new prodromal cohort

PPMI has launched a new study arm to enroll and follow a prodromal PD cohort with the goal of providing researchers with the opportunity to examine biomarker progression prior to the onset of motor symptoms. This new cohort seeks to enroll subjects without Parkinson?s disease who have at least one of the following characteristics: hyposmia, REM sleep behavior disorder, LRRK2 genetic mutation.

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Update on New Prodromal Cohort Added to PPMI

This March, the Parkinson?s Progression Markers Initiative (PPMI) will launch a new study arm to enroll and follow a prodromal Parkinson?s disease (PD) cohort.   Defining a pre-diagnostic or prodromal phase for PD presents both an immediate challenge ? how to reliably identify individuals during this prodromal period at high risk to phenoconvert to PD ? […]

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PPMI study to add a new prodromal cohort

The PPMI Steering Committee has recently decided to expand PPMI to include a prodromal PD cohort.  Defining a pre-diagnostic or prodromal phase for PD presents both an immediate challenge ? how to reliably identify individuals during this prodromal period at high risk to phenoconvert to PD ? and an eventual opportunity:  can we ultimately treat […]

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PPMI 2012 Annual Meeting Summary

The PPMI Annual Meeting recently took place in New York City. Access to the presentations that were made at the meeting are now available.

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