Tag Archive | "CSF"

New Feature: PPMI Biospecimen Inventory

An inventory of available biospecimens in PPMI can now be accessed on www.ppmi-info.org. This regularly updated table reflects the number of samples that are currently available for analysis by visit and type of sample. This is a key tool for researchers looking to request specimens to be analyzed for biomarker verification studies. This inventory table now provides researchers with real-time numbers of specimens available before submitting a request.

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MJFF Funding for Data & Biospecimen analysis, including PPMI

Qualified researchers may now request access to clinical data and biospecimens from a collection of studies exploring promising areas in Parkinson?s research, including PPMI. The Michael J Fox Foundation for Parkinson's Research (MJFF) is also offering funding for use and analysis of the available information and materials to progress therapeutic and disease-modifying treatments. In December, MJFF will conduct its final review of this year's submissions for access to biospecimens or data and for grants of up to $250,000 over two years.

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Op-Ed in Scientific American by MJFF CEO Todd Sherer highlights PPMI

This week, Scientific American published an Op-Ed by Todd Sherer, PhD, Chief Executive Office of The Michael J Fox Foundation for Parkinson's Research. The op-ed is a call to action for researchers to continue investigating the promising leads already discovered, and to expand the existing strategies in PD research through collaboration. Dr. Sherer highlights the recent PPMI results published in JAMA Neurology as a "critical milestone in pursuit of biomarkers that could lead to swifter diagnosis and drug development"

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MJFF CEO Todd Sherer discusses PPMI in Medscape interview

Todd Sherer, PhD, Chief Executive Office of The Michael J Fox Foundation for Parkinson's Research, was recently interviewed by Medscape about PPMI and other promising PD research. Dr. Sherer discusses the goal of PPMI, as well as the recent publication in JAMA Neurology using PPMI data that gives evidence of proteins in the CSF levels of which were lower in people with early PD compared with age- and gender-matched controls.

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First study results featured in USA Today, Time, & Medscape

The first major study results from PPMI were recently highlighted in several national news outlets. USA Today, Time, and Medscape featured the study, which was published in the journal JAMA Neurology. Researchers sought to evaluate the baseline characteristics and relationship to clinical features of CSF biomarkers in de novo PD subjects and healthy controls enrolled in PPMI.

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First major PPMI results published in JAMA Neurology

The first major study results were published in the journal JAMA Neurology. Researchers sought to evaluate the baseline characteristics and relationship to clinical features of CSF biomarkers in de novo PD subjects and healthy controls enrolled in PPMI. They found that measures of CSF A?1-42, T-tau, P-tau181, and ?-synuclein have prognostic and diagnostic potential in early-stage PD. Further investigations using the entire PPMI cohort will test the predictive performance of CSF biomarkers for PD progression.

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SciBX report on MJFF’s progress in biomarkers features PPMI

Last week, the Science-Business eXchange (SciBX) published an article on the availability of data and biospecimens from several studies sponsored by The Michael J. Fox Foundation for Parkinson's Research (MJFF), including PPMI. The article also focuses on the preliminary findings in CSF proteins in PPMI, as well as the potential for overlap with Alzheimer's disease.

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New publication on CSF biomarkers features PPMI data

Les Shaw and John Q. Trojanowski, Co-PI's of the PPMI Bioanalytics Core, are co-authors on a paper published in Acta Neuropathologica that used both PPMI and ADNI data to look at correlations between CSF biomarkers and cognitive impairment.

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PPMI subject of Podcast featured on MichaelJFox.org

On June 6th, 2013, PPMI was featured on The Michael J Fox Foundation for Parkinson's Research Foxfeed Blog. MJFF Contributing Editor Dave Iverson interviewed the Foundation's Vice President of Research Programs Mark Frasier, PhD in a podcast with the goal of informing patients about some of the preliminary findings of PPMI.

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Select Preliminary Baseline Data for 90% of Cohort Recruited is Presented at AAN

PPMI senior leadership presented PPMI data collected so far at the American Academy of Neurology?s 75th annual meeting. The poster used baseline data to give a preliminary sense of the characteristics of the PPMI cohort. The poster also highlights CSF acquisition success rates in PPMI and data from baseline DaTSCANs.

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