Tag Archive | "Blood/Serum"

MJFF Funding for Data & Biospecimen analysis, including PPMI

Qualified researchers may now request access to clinical data and biospecimens from a collection of studies exploring promising areas in Parkinson?s research, including PPMI. The Michael J Fox Foundation for Parkinson's Research (MJFF) is also offering funding for use and analysis of the available information and materials to progress therapeutic and disease-modifying treatments. In December, MJFF will conduct its final review of this year's submissions for access to biospecimens or data and for grants of up to $250,000 over two years.

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PPMI data presented in four posters at the MDS 2013 International Congress

On June 17th & 18th, data from PPMI was featured in four posters at the Movement Disorder Society's 2013 International Congress in Sydney, Australia.

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MDS 2013 Poster: ?Relationship between Serum Urate and Clinical Features in Early Parkinson?s Disease: PPMI Baseline Data?

A poster submitted by Radu Constantinescu, MD of the Center for Human Experimental Therapeutics (CHET) at the University of Rochester Medical Center has been accepted for the poster session at the Movement Disorder Society?s International Congress this June in Sydney, Australia.

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PPMI Biospecimens Keep Rolling In: An Inventory of the 2,755 Samples Collected to Date

See the actual numbers of samples of CSF, urine, RNA, serum and plasma that have been collected in PPMI to date.

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New Blood test for Parkinson’s is being studied

The company Durin Technologies has identified a panel of protein biomarkers in the blood of Parkinson?s disease subjects that seem to be different compared to controls and Alzheimer?s disease. It is unknown whether the proteins change with the course of the disease but MJFF is supporting the company to verify these results in samples collected in the DATATOP clinical trial to explore this question. If results are promising the PPMI cohort would be a good sample set in which to verify the observation and build the dataset for the biomarker panel.

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Qualification study in healthy volunteers prompts investigators to explore fluctuation of markers in PD subjects

PPMI study leadership is repeating a qualification study in controls that was completed last fall with a group of PD subjects and older controls to detect changes in biomarkers over the course of a day.

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PPMI study will now include collection of whole blood, DTI and resting state fMRI

Based on new data and findings, the PPMI Steering Committee is integrating new tests and assessments into the study.

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Study finds that plasma EGF levels predict cognitive decline (Ann Neurol)

A recent study published in Annals of Neurology showed that plasma epidermal growth factor (EGF) levels correlated to cognitive test scores in PD patients, and may be used as a biomarker for cognitive decline in PD. Among the authors are several PPMI Steering Committee Members.

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Preliminary information posted about CSF and DJ-1 qualification study

Learn about the qualification study that was completed during the planning phase for PPMI to assess the test/re-test reliability and diurnal fluctuations for select lead biomarker candidates.

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