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PPMI Steering Committee Paper Accepted to Movement Disorders Journal

Apr 5, 2018

We are excited to announce a recent research article using longitudinal data from PPMI has been accepted to Movement Disorders.  Members of the PPMI Steering Committee, including Dr. Tanya Simuni of Northwestern University, authored this publication on behalf of PPMI. The study, entitled “Longitudinal Change of Clinical and Biological Measures in Early Parkinson’s Disease: Parkinson’s […]

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PPMI Study Update Call – 3/15/18

Feb 21, 2018

PPMI Study Update Call Thursday, March 15 12-1 pm Eastern Time Andrew Siderowf, MD, MSCE Professor of Neurology University of Pennsylvania Co-Principal Investigator of PPMI   PPMI participants are encouraged to call in to the next quarterly Study Update Call on Thursday, March 15, 2018 at 12 pm EST.  During this call, Dr. Andrew Siderowf, […]

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PPMI at MDS 2017

May 30, 2017

The 21st International Congress of Parkinson’s Disease and Movement Disorders (MDS) conference will take place next week, June 4-8, in Vancouver, Canada. PPMI leadership is happy to announce that several posters will feature PPMI data. We invite you to look for PPMI at this year’s meeting:   Blue Ribbon Highlight:  840 “Multiple modality biomarker prediction […]

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PPMI iPSC Lines — A Valuable Tool for Researchers

Mar 23, 2017

The Parkinson’s Progression Markers Initiative (PPMI) has expanded to include the generation of induced pluripotent stem cell (iPSC) lines from reprogrammed peripheral mononuclear blood cells (PBMCs) collected from PPMI participants. Study leadership hopes to complete 135 blood collections by the end of 2017; to date, over 50 PPMI participants have given blood samples. Cells lines […]

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Live Webinar February 24: 2016 PPMI Data Challenge Winners

Feb 9, 2017

In June of 2016, The Michael J. Fox Foundation challenged data scientists and computational analysts to work with PPMI’s unprecedented collection of open-access clinical, molecular, and imaging data to answer two fundamental questions about Parkinson’s disease: what are the subtypes of the disease, and what baseline factors predict disease progression? In total, forty researchers submitted […]

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The Michael J. Fox Foundation Announces $25,000 PPMI Data Challenge to Advance Parkinson’s Understanding and Study Design

Jun 8, 2016

Today The Michael J. Fox Foundation (MJFF) announced a challenge asking data scientists and computational analysts to work with researchers to answer fundamental questions about Parkinson’s that limit our understanding and slow drug testing. The PPMI Data Challenge offers $25,000 each to two teams that develop models to answer either: • What factors at baseline predict […]

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2016 PPMI Annual Meeting held in New York City

May 20, 2016

The 2016 PPMI annual meeting took place on May 4-5 in New York City.  The meeting brought together 175 PPMI stakeholders from around the world, including PPMI leadership, site principal investigators, site coordinators and industry partners.  During the two day meeting, there was discussion of the data coming out of PPMI to date, plans for the […]

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PPMI Q1 2016 Study Update call

Mar 31, 2016

On March 11, Dr. Mark Frasier, Senior Vice President at the Michael J. Fox Foundation, shared an update on the PPMI study. Dr. Frasier summarized some of the key accomplishments of PPMI to date.

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Researchers identify biomarker for early cognitive decline in Parkinson’s disease patients using PPMI data

Feb 25, 2016

Many patients with Parkinson’s Disease (PD) develop mild cognitive impairment (MCI) or dementia. Identifying biomarkers for cognitive impairment could be instrumental in facilitating both early diagnosis of MCI and developing new cognitive-enhancing treatments. New research using PPMI data published in the Journal of Parkinson’s Disease indicates that lower concentrations of ?-synuclein in cerebrospinal fluid (CSF) is associated with reduced performance on several cognitive tests.

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Dr. Omar El-Agnaf to use PPMI biospecimens for validation of cerebral spinal fluid ?-synuclein species as surrogate biomarkers for Parkinson’s disease

Feb 15, 2016

We are excited to announce another recent approval by our Biospecimen Review Committee. Dr. Omar El-Agnaf, Professor at Hamad Bin Khalifa University in Doha, Qatar, will be using PPMI biospecimens for a project entitled: Validation of CSF ?-synuclein species as surrogate biomarkers for Parkinson’s disease. Dr. El-Agnaf has recently reported higher levels of the oligomeric […]

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