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Live Webinar February 24: 2016 PPMI Data Challenge Winners

Feb 9, 2017

In June of 2016, The Michael J. Fox Foundation challenged data scientists and computational analysts to work with PPMI’s unprecedented collection of open-access clinical, molecular, and imaging data to answer two fundamental questions about Parkinson’s disease: what are the subtypes of the disease, and what baseline factors predict disease progression? In total, forty researchers submitted […]

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2016 PPMI Annual Meeting held in New York City

May 20, 2016

The 2016 PPMI annual meeting took place on May 4-5 in New York City.  The meeting brought together 175 PPMI stakeholders from around the world, including PPMI leadership, site principal investigators, site coordinators and industry partners.  During the two day meeting, there was discussion of the data coming out of PPMI to date, plans for the […]

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Researchers identify biomarker for early cognitive decline in Parkinson’s disease patients using PPMI data

Feb 25, 2016

Many patients with Parkinson’s Disease (PD) develop mild cognitive impairment (MCI) or dementia. Identifying biomarkers for cognitive impairment could be instrumental in facilitating both early diagnosis of MCI and developing new cognitive-enhancing treatments. New research using PPMI data published in the Journal of Parkinson’s Disease indicates that lower concentrations of α-synuclein in cerebrospinal fluid (CSF) is associated with reduced performance on several cognitive tests.

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Diffusion Tensor Imaging Reflects Degree of Motor Symptoms

Jul 13, 2015

In a recent publication in Movement Disorders, Zhang, et al. used PPMI data and found that diffusion tensor imaging (DTI) detected neural fiber abnormalities in people with Parkinson's disease (PD) and that the degree of deviation from normal neural fiber integrity is associated with the severity of motor symptoms in patients.

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Biospecimen Analysis Call for Participants Posted

Jun 22, 2015

Dr. Mollenhauer: "[Cerebrospinal fluid] bears the possibility to reflect the underlying biology of the disease process." Find out what makes the PPMI biospecimens, like cerebrospinal fluid, so important to finding progression markers for PD.

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PPMI at MDS 2015

Jun 12, 2015

PPMI is excited to announce that several presentations at the 19th International Congress of Parkinson's Disease and Movement Disorders (MDS) will feature PPMI data. View the PPMI-related abstracts for this congress happening in San Diego, California on June 14-18.

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PPMI Annual Meeting 2015 Summary

Jun 11, 2015

Nearly 150 PPMI investigators, coordinators, study cores, patient advisory and steering committee members, sponsors, and industry partners from around the world met in New York City May 13-14, 2015 to share PPMI updates and to discuss the future of the initiative. View the meeting's presentations.

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Morphological Changes in the PD Brain

Jun 9, 2015

Frontiers in Neuroscience recently published an article by Garg, et al. comparing changes in the volume of different regions of the brain between healthy controls and people with Parkinson's using structural MRIs from PPMI and the University of British Columbia.

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AD/PD & AAN Presentations Posted

Jun 9, 2015

With the PPMI data set and biospecimen sample inventory rapidly growing, PPMI data is increasingly being presented around the globe. View some highlights of PPMI data presentations from this past season.

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SWEDDs and Nonmotor Symptoms Publication

May 11, 2015

In a recent paper in Movement Disorders, researchers sought to better understand SWEDDs compared to people with Parkinson's and healthy controls (HCs) by comparing the nonmotor symptoms for each group using the PPMI baseline data. Certain symptoms, like orthostatic hypotension, were found to be more common in SWEDDs than in PD participants.

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