Study Cores

Principal Investigator

Ken Marek, MD, President and Senior Scientist, Institute of Neurodegenerative Disorders

Study Cores

Bioanalytics Core

The Bioanalytics Core will perform some of the biomarker verification studies identified by the Steering Committee and will be working closely with the PPMI Biorepository in monitoring and performing quality control on collected samples.

Co-Investigators: John Q. Trojanowski, MD, PhD and Leslie M. Shaw, PhD
Department of Pathology and Laboratory Medicine
University of Pennsylvania School of Medicine

Bioinformatics Core

The Bioinformatics Core has designed and will maintain the PPMI study database. This Core is also responsible for the programming of the study Web site.

Principal Investigator: Arthur W. Toga, PhD
Laboratory of Neuro Imaging (LONI)

Biorepository Core

The PPMI Biorepository will receive, store and distribute biospecimens collected throughout the course of the study.

Principal Investigator: Dorit Berlin, PhD
Coriell Institute for Medical Research

Clinical Core

The Clinical Core is responsible for site management, as well as the collection, tracking and performance of quality control on clinical data.

Principal Investigator: Karl Kieburtz, MD, MPH
Clinical Trials and Coordination Center (CTCC)
University of Rochester

DTI Analysis Core

The DTI Analysis Core will lead the analyses that will be performed on the MRI/DTI data.

Principal Investigator: Norbert W. Schuff, PhD
VA Medical Center San Francisco
Department of Radiology & Biomedical Imaging, University of California San Francisco

Genetics Core

The Genetics Core will analyze DNA collected from study subjects.

Principal Investigator: Andrew Singleton, PhD
Laboratory of Neurogenetics
National Institute on Aging/NIH

Imaging Core

The Imaging Core will receive, aggregate and perform quality control on all imaging data in the study. This Core will also perform preliminary analyses of imaging data, as directed by the Steering Committee.

Principal Investigator: John Seibyl, MD
Institute of Neurodegenerative Disorders

Smell Core

The smell core provides the operational support for the hyposmia testing for the prodromal cohort of the study.

Principal Investigator: Danna Jennings, MD
Institute of Neurodegenerative Disorders

Statistics Core

The Statistics Core will lead the statistical analyses that will be performed on the PPMI data and samples.

Principal Investigator: Christopher S. Coffey, PhD
Clinical Trials Statistical and Data Management Center
University of Iowa

Genetics Coordination Core

The Genetics Coordination Core provides operational support for the Genetic Cohort of the study.

Principal Investigator: Tatiana Foroud, PhD
Department of Medical and Molecular Genetics
Indiana University School of Medicine

RBD Core

The RBD Core reviews PSG data for the Prodromal Cohort.

Principal Investigator: Geert Mayer, MD
Hephata Hessisches Diakoniezentrum
Chefarzt der Hephata-Klinik

To communicate with a Principal Investigator at one of the Study Cores, Contact Us.

Sponsoring Organization

PPMI is sponsored by The Michael J. Fox Foundation for Parkinson’s Research, which is coordinating all study activities and working closely with the Principal Investigator and Study Cores.

Sohini Chowdhury, Senior Vice President, Research Partnerships
Katie Kopil, PhD, Associate Director, Research Programs
Mark Frasier, PhD, Vice President, Research Programs
Claire Meunier, Director, Clinical Trial Strategies
Todd Sherer, PhD, Chief Executive Officer
Vanessa Arnedo, Associate Director, Research Partnerships